SCHEMBL29461553

SCHEMBL29461553

CN(C)CCNc1ccc2c3c1cccc3c(=O)n1c3ccccc3nc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 1/20 0.55
▸ KMT2A Q03164 4/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ CAMKK1 Q8N5S9 2/20 0.54
▸ CAMKK2 Q96RR4 2/20 0.54
▸ CYP1A2 P05177 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ CASP1 P29466 2/20 0.54
▸ CASP7 P55210 2/20 0.54
▸ CYP2D6 P10635 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ CSNK2A2 P19784 1/20 0.54
▸ CSNK2B P67870 1/20 0.54
▸ CSNK2A1 P68400 1/20 0.54
▸ PIM3 Q86V86 1/20 0.54
▸ DYRK2 Q92630 1/20 0.54
▸ MKNK1 Q9BUB5 1/20 0.54
▸ PIM2 Q9P1W9 1/20 0.54
▸ NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16863801 1.00 BCL2 (0.55) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL30278153 0.90 BCL2 (0.53) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL12687849 0.86 KMT2A (0.60) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL12687844 0.83 BCL2 (0.57) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL16574973 0.82 BCL2 (0.54) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL12478636 0.82 BCL2 (0.68) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL13229867 0.81 BCL2 (0.50) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL20110593 0.79 KMT2A (0.63) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL20117736 0.79 NQO2 (0.46) BCL2KMT2AMEN1CAMKK1CAMKK2
SCHEMBL29422905 0.77 KMT2A (0.66) BCL2KMT2AMEN1CAMKK1CAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11371085-B2 Reagents and methods for isothermal chain reaction MANCEBO RICARDO (US) 2022-06-28 — — US claimed
CN-122095108-A Multiplex detection combinations for detecting viral, bacterial and parasitic nucleic acids — 2026-05-26 — — CN disclosed
US-12637724-B2 Compositions, kits and methods for detection of viral sequences Life Technologies Corporation (US) 2026-05-26 — — US disclosed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 — — US disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 — — US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 — — US disclosed
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-04-23 — — US disclosed
US-12595508-B2 Nucleotide cleavable linkers and uses thereof Singular Genomics Systems, Inc. (US) 2026-04-07 — — US disclosed
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-03-26 — — US disclosed
US-12577271-B2 Modified nucleotides and uses thereof Singular Genomics Systems, Inc. (US) 2026-03-17 — — US disclosed
US-11359232-B2 Reagents and methods for autoligation chain reaction Mancebo, Ricardo (US) 2022-06-14 — — US disclosed
US-20220170092-A1 METHODS FOR LONG READ SEQUENCING FIRST-CITIZENS BANK & TRUST COMPANY 2022-06-02 — — US disclosed
EP-3997101-A1 NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-05-18 — — EP disclosed
CN-107760770-B Compositions, methods and kits for nucleic acid synthesis and amplification 生命技术公司 2022-05-17 — — CN disclosed
US-20220127299-A1 NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF LG ELECTRONICS INC. (KR) 2022-04-28 — — US disclosed
US-20220119780-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2022-04-21 — — US disclosed
US-20220119873-A1 KARYOTYPING ASSAY Life Technologies Corporation 2022-04-21 — — US disclosed
US-20220119779-A1 MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2022-04-21 — — US disclosed
WO-2022072374-A1 LIGHT-CONTROLLED BIOORTHOGONAL TETRAZINE LIGATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-07 — — WO disclosed
US-11266673-B2 Nucleotide derivatives and methods of use thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637724-B2 Compositions, kits and methods for detection of viral sequences SARS1, POLL, DDX41 BCL2 3132/4885KMT2A 1790/4885MEN1 2544/4885
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ BCL2 4655/4885KMT2A 308/4885MEN1 3513/4885
US-12595508-B2 Nucleotide cleavable linkers and uses thereof NSUN2, CCRL2, NOP2 BCL2 1244/4885KMT2A 2804/4885MEN1 4378/4885
US-12577271-B2 Modified nucleotides and uses thereof NUDT1, NSUN2, CCRL2 BCL2 1812/4885KMT2A 2809/4885MEN1 2476/4885
US-12637489-B2 Silicon containing modified nucleotide analogs NSUN2, POLR2H, POLH BCL2 2182/4885KMT2A 2375/4885MEN1 2394/4885
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF POLL, POLB, POLN BCL2 3651/4885KMT2A 1209/4885MEN1 3638/4885
US-20220127299-A1 NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF NUDT21, CPSF7, DCLRE1A BCL2 3247/4885KMT2A 1435/4885MEN1 2454/4885
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF POLB, POLM, POLRMT BCL2 4392/4885KMT2A 1696/4885MEN1 1571/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM BCL2 4790/4885KMT2A 755/4885MEN1 2077/4885
US-11266673-B2 Nucleotide derivatives and methods of use thereof POLRMT, NSUN2, NUDT1 BCL2 4476/4885KMT2A 1863/4885MEN1 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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