SCHEMBL30455472

SCHEMBL30455472

C[C@H](NC(=O)CNC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.39
▸ REN P00797 8/20 0.38
▸ CMA1 P23946 1/20 0.36
▸ OPRM1 P35372 1/20 0.36
▸ OPRD1 P41143 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468867 1.00 GRB2 (0.39) GRB2RENCMA1OPRM1OPRD1
SCHEMBL29468784 0.93 REN (0.46) GRB2RENOPRM1OPRD1
SCHEMBL29375930 0.88 OPRM1 (0.43) GRB2RENOPRM1OPRD1
SCHEMBL29376028 0.88 OPRM1 (0.43) GRB2RENOPRM1OPRD1
SCHEMBL30543475 0.87 GRB2 (0.41) GRB2CMA1OPRM1OPRD1KMT2A
SCHEMBL30414346 0.87 GRB2 (0.42) GRB2CMA1OPRM1OPRD1KMT2A
SCHEMBL29468804 0.86 GRB2 (0.41) GRB2CMA1OPRM1OPRD1KMT2A
SCHEMBL29468889 0.85 GRB2 (0.42) GRB2CMA1OPRM1OPRD1KMT2A
SCHEMBL31140016 0.85 CAPN1 (0.41) GRB2RENOPRM1OPRD1
SCHEMBL30013216 0.85 CAPN1 (0.41) GRB2RENOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications SHENZHEN TURIER BIOTECH CO., LTD (CN) 2023-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications IAPP, PNLIP, DPP4 GRB2 1679/4885REN 26/4885CMA1 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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