SCHEMBL2947003

SCHEMBL2947003

CCc1cc(-c2ccc(OC)cc2)ccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPT P10636 5/20 0.44
LMNA P02545 3/20 0.44
APP P05067 1/20 0.44
CHEK1 O14757 1/20 0.44
MERTK Q12866 1/20 0.43
MAPK1 P28482 3/20 0.43
HPGD P15428 2/20 0.43
RAF1 P04049 1/20 0.43
GFER P55789 1/20 0.43
PAX8 Q06710 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 1/20 0.42
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3105068 0.87 SMN1; SMN2 (0.51) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL1663978 0.83 ALDH1A1 (0.54) HTR7SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL2950974 0.82 CRHBP (0.50) KMT2AALDH1A1MAPTAPPHPGD
SCHEMBL16284336 0.82 TSHR (0.52) RAB9AKMT2AALDH1A1MAPTCHEK1
SCHEMBL1307865 0.80 ABCB1 (0.52) HTR7SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL15173740 0.80 TLR4 (0.52) SMN1; SMN2NPC1RAB9AKMT2AALDH1A1
SCHEMBL28874514 0.79 ALOX5 (0.57) HTR7SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL4330380 0.79 MAPT (0.56) HTR7SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL19396234 0.79 HTR7 (0.44) HTR7SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL2955956 0.78 CA1 (0.41) NPC1RAB9AKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140362545-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME Innolux Corporation (TW) 2014-12-11 US disclosed
US-8445734-B2 Photolabile protective groups for improved processes to prepare oligonucleotide arrays NIGU CHEMIE GMBH (DE) 2013-05-21 US disclosed
US-20100292458-A1 NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS NIGU CHEMIE GMBH (DE) 2010-11-18 US disclosed
US-7759513-B2 Photolabile protective groups for improved processes to prepare oligonucleotide arrays NIGU CHEMIE GMBH (DE) 2010-07-20 US disclosed
US-20040175741-A1 Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays NIGU CHEMIE GMBH (DE) 2004-09-09 US disclosed
WO-2004074300-A2 NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS NIGU CHEMIE GMBH (DE) 2004-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292458-A1 NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS NT5C3B, NSUN2, ERCC4 HTR7 1527/4885SMN1; SMN2 2633/4885NPC1 4108/4885
US-20040175741-A1 Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays NT5C3B, NSUN2, DCLRE1B HTR7 1693/4885SMN1; SMN2 2967/4885NPC1 4179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.