Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473445 | 0.80 | MAOA (0.58) | MAOBMAOAALDH1A1CES2CES1 | |
| SCHEMBL29473471 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTCES2CES1 | |
| SCHEMBL2491983 | 0.79 | L3MBTL1 (0.63) | MAOBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL27579430 | 0.79 | MAOA (0.55) | MAOBMAOAKDM4EALDH1A1LMNA | |
| SCHEMBL29473444 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL29473434 | 0.76 | CA1 (0.58) | MAPTCES2CES1GSK3BALOX15 | |
| SCHEMBL29473446 | 0.76 | PLK1 (0.50) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL26344003 | 0.75 | MAOA (0.57) | MAOBMAOAKDM4EALDH1A1LMNA | |
| SCHEMBL11056976 | 0.73 | KMT2A (0.60) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL22504118 | 0.73 | LMNA (0.50) | MAOBKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156668-B | Method for synthesizing 4-polyfluoroalkyl-2, 6-diaryl substituted pyridine compound | 福州大学 | 2022-04-26 | — | — | CN | disclosed |