Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905442 | 0.84 | MAOA (0.46) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL3695975 | 0.79 | CES2 (0.60) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL2448732 | 0.79 | L3MBTL1 (0.52) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL28552018 | 0.79 | L3MBTL1 (0.61) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL29235126 | 0.79 | GPR139 (0.58) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL29473459 | 0.75 | MAOB (0.58) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL10673423 | 0.75 | MAOA (0.57) | MAOAMAOBCES2CES1MAPT | |
| SCHEMBL599285 | 0.74 | KMT2A (0.74) | CES2CES1MAPTL3MBTL1NPC1 | |
| SCHEMBL11606610 | 0.74 | KMT2A (0.74) | CES2CES1MAPTL3MBTL1NPC1 | |
| SCHEMBL14119105 | 0.74 | CES2 (0.65) | MAOBCES2CES1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4248957-A1 | METHOD FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS THROUGH CO-ADMINISTRATION OF CURCUMIN DERIVATIVE AND TGF-? RECEPTOR INHIBITOR | University Industry Foundation, Yonsei University Wonju Campus (KR) | 2023-09-27 | — | — | EP | disclosed |