Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518592 | 0.72 | ALDH1A1 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL5180701 | 0.69 | TSHR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL1506376 | 0.69 | TSHR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL15513854 | 0.69 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL9949118 | 0.69 | LMNA (0.65) | HDAC11SLC6A3LMNATSHRNFKB1 | |
| Adipic Acid SCHEMBL8654409 | 0.69 | LMNA (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL27479224 | 0.68 | LMNA (0.85) | HDAC11LMNATSHRNFKB1PMP22 | |
| Resorcinol SCHEMBL8652804 | 0.67 | HDAC6 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Resorcinol SCHEMBL8651630 | 0.67 | HDAC6 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Resorcinol SCHEMBL8650701 | 0.67 | HDAC6 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399306-A | Copolymerization of polyamide polymers, extrusion and forming filaments into yarns | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| US-10618718-B2 | Oxygen scavengers | APG Polytech, LLC (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190233195-A1 | OXYGEN SCAVENGERS | APG Polytech, LLC (US) | 2019-08-01 | — | — | US | disclosed |
| EP-2748084-B1 | ARTICLES CONTAINING OXYGEN-SCAVENGING MATERIALS | APG POLYTECH LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-10207853-B2 | Oxygen scavengers | APG Polytech, LLC (US) | 2019-02-19 | — | — | US | disclosed |
| US-10052525-B2 | Dual core golf ball having positive-hardness-gradient thermoplastic inner core and positive-hardness-gradient thermoset outer core layer | ACUSHNET COMPANY | 2018-08-21 | — | — | US | disclosed |
| US-9999809-B2 | Dual core having thermoplastic inner core, thermoset outer core layer, and positive hardness gradient | ACUSHNET COMPANY (US) | 2018-06-19 | — | — | US | disclosed |
| US-9925422-B2 | Golf ball having a thermoplastic positive hardness gradient inner core layer and a thermoset shallow positive hardness gradient outer core layer | ACUSHNET COMPANY (US) | 2018-03-27 | — | — | US | disclosed |
| US-9873026-B2 | Thermoplastic dual core having positive hardness gradient inner and outer core layers | ACUSHNET COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9789367-B2 | Thermoplastic dual core having a negative gradient inner core and a positive gradient outer core | ACUSHNET COMPANY (US) | 2017-10-17 | — | — | US | disclosed |
| US-20050119446-A1 | Production method of polyamide | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1418193-A1 | Production method of polyamides | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-6733853-B2 | BLEND OF A POLYAMIDE RESIN CONTAINING A PHOSPHORUS COMPOUND A POLYESTER RESIN CONTAINING AN ANTIMONY COMPOUND; POLYAMIDE BASED ON M-XYLYLENE-DIAMINE AND ADIPIC ACID IMPROVED IN GAS BARRIER PROPERTIES; DISCOLORATION INHIBITION; PACKAGING | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-1400568-A1 | Polyester-based resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-20040054053-A1 | Polyester-based resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-20020165326-A1 | Blend of a polyamide resin containing a phosphorus compound a polyester resin containing an antimony compound; polyamide based on m-xylylene-diamine and adipic acid improved in gas barrier properties; discoloration inhibition; packaging | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-11-07 | — | — | US | disclosed |
| EP-1239008-A1 | Polyester-based resin composition and shaped articles | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0086653-B1 | PHOTOSENSITIVE RESIN COMPOSITION | Toyo Boseki Kabushiki Kaisha (JP) | 1987-02-04 | — | — | EP | disclosed |
| US-4544624-A | Photosensitive resin composition | TOYO BOSEKI KABNUSHIKI KAISHA (JP) | 1985-10-01 | — | — | US | disclosed |
| EP-0086653-A2 | Photosensitive resin composition | Toyo Boseki Kabushiki Kaisha (JP) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10207853-B2 | Oxygen scavengers | LPO, GPX4, GPX1 | SLC6A3 1404/4885HDAC3 3748/4885HDAC4 4599/4885 |
| US-20190233195-A1 | OXYGEN SCAVENGERS | LPO, GPX4, GPX1 | SLC6A3 1404/4885HDAC3 3748/4885HDAC4 4599/4885 |
| US-10618718-B2 | Oxygen scavengers | LPO, GPX4, GPX1 | SLC6A3 1404/4885HDAC3 3748/4885HDAC4 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.