Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839242 | 1.00 | ALDH1A1 (0.74) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL31072915 | 0.99 | ALDH1A1 (0.72) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| SCHEMBL6613815 | 0.82 | RAB9A (0.59) | ALDH1A1MAPTRAB9ANPC1TSHR | |
| SCHEMBL22580172 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| SCHEMBL30753604 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| SCHEMBL23933096 | 0.81 | TDP1 (1.00) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| SCHEMBL19090370 | 0.80 | TDP1 (0.73) | ALDH1A1TDP1MAPTRAB9ANPC1 | |
| SCHEMBL324560 | 0.79 | GAA (0.54) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL18292466 | 0.79 | L3MBTL1 (0.78) | ALDH1A1MAPTRAB9ANPC1TSHR | |
| SCHEMBL18292431 | 0.79 | L3MBTL1 (0.71) | ALDH1A1TDP1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024185438-A1 | AZIDE COMPOUND, AMINE COMPOUND, AND METHOD FOR PRODUCING EDOXABAN | 株式会社カネカ | 2024-09-12 | — | — | WO | disclosed |
| US-10758522-B2 | Small molecule analogs of the nemo binding peptide | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-01 | — | — | US | disclosed |
| US-10758522-B2 | Small molecule analogs of the nemo binding peptide | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-01 | — | — | US | disclosed |
| US-20180169078-A1 | Small Molecule Analogs of the Nemo Binding Peptide | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-06-21 | — | — | US | disclosed |
| US-20180169078-A1 | Small Molecule Analogs of the Nemo Binding Peptide | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-06-21 | — | — | US | disclosed |
| WO-2016196117-A1 | SMALL MOLECULE ANALOGS OF THE NEMO BINDING PEPTIDE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-12-08 | — | — | WO | disclosed |
| US-7737161-B2 | Condensed furan compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7531537-B2 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| CN-100344632-C | Fused furan compound | TANABE SEIYAKU CO (JP) | 2007-10-24 | — | — | CN | disclosed |
| US-20060247273-A1 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1666478-A1 | CARBAMOYL-TYPE BENZOFURAN DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20060094724-A1 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1723210-A | Fused furan compound | TANABE SEIYAKU CO (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-20050282808-A1 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-12-22 | — | — | US | disclosed |
| EP-1582521-A1 | FUSED FURAN COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-1489078-A1 | BENZOFURAN DERIVATIVE | Tanabe Seiyaku Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282808-A1 | Benzofuran derivative | F12, F2, F11 | ALDH1A1 683/4885TDP1 3656/4885MAPT 4700/4885 |
| US-10758522-B2 | Small molecule analogs of the nemo binding peptide | IKBKG, NFKBIA, NFKB1 | ALDH1A1 4340/4885TDP1 745/4885MAPT 932/4885 |
| US-20060247273-A1 | Carbamoyl-type benzofuran derivatives | F12, F2, F3 | ALDH1A1 1153/4885TDP1 3481/4885MAPT 4544/4885 |
| US-20060094724-A1 | Fused furan compound | F2, F12, F11 | ALDH1A1 1674/4885TDP1 4423/4885MAPT 4835/4885 |
| US-20180169078-A1 | Small Molecule Analogs of the Nemo Binding Peptide | IKBKG, NFKBIA, NFKB1 | ALDH1A1 4340/4885TDP1 745/4885MAPT 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.