Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | REN | P00797 | 4/20 | 0.50 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666870 | 0.90 | ACE (0.52) | ACERENCALCRLKDM4EF2 | |
| SCHEMBL30792488 | 0.89 | ACE (0.49) | ACERENCALCRLKDM4EF2 | |
| SCHEMBL30579777 | 0.89 | ACE (0.51) | ACERENCALCRL | |
| SCHEMBL30435421 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL9471485 | 0.87 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL10428029 | 0.87 | KEAP1 (0.47) | CALCRL | |
| SCHEMBL30435869 | 0.86 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL9705671 | 0.85 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL27953019 | 0.85 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL9705665 | 0.85 | ACE (0.48) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366745-A1 | TROPICAL DISEASE VACCINES | MODERNATX, INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-20220257746-A1 | TROPICAL DISEASE VACCINES | MODERNATX, INC. (US) | 2022-08-18 | — | — | US | disclosed |
| US-11278611-B2 | Zika virus RNA vaccines | MODERNATX, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278611-B2 | Zika virus RNA vaccines | RBM3, NSUN3, RBM12 | ACE 524/4885REN 3541/4885CALCRL 4053/4885 |
| US-20220257746-A1 | TROPICAL DISEASE VACCINES | MTREX, DDX5, DIS3 | ACE 514/4885REN 2758/4885CALCRL 3353/4885 |
| US-20240366745-A1 | TROPICAL DISEASE VACCINES | MTREX, DDX5, DIS3 | ACE 514/4885REN 2758/4885CALCRL 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.