Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.62 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.62 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332528 | 1.00 | PLOD2 (0.62) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL2424897 | 0.85 | LMNA (0.65) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL11161284 | 0.81 | ROCK2 (0.66) | LMNACYP3A4ALDH1A1GAAHIF1A | |
| Niacin SCHEMBL4718565 | 0.81 | ALDH1A1 (0.78) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL31703901 | 0.80 | LMNA (0.69) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL29704465 | 0.80 | LMNA (0.59) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL800635 | 0.80 | LMNA (0.69) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| SCHEMBL27500194 | 0.79 | LMNA (0.62) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| Niacin SCHEMBL28362910 | 0.78 | ALDH1A1 (0.72) | PLOD2PLOD3PLOD1LMNACYP1A2 | |
| Niacinamide SCHEMBL30011021 | 0.78 | F7 (0.76) | PLOD2PLOD3PLOD1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225442-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Unichem Laboratories Ltd (IN) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022074572-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | UNICHEM LABORATORIES LTD (IN) | 2022-04-14 | — | — | WO | disclosed |