Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948463 | 0.86 | KDM4E (0.51) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL15858742 | 0.80 | PLG (0.34) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL18503114 | 0.80 | HPGD (0.40) | NPC1RAB9AKMT2ATSHRHPGD | |
| SCHEMBL24716058 | 0.79 | KDM4E (0.56) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL12717045 | 0.77 | ADORA2A (0.45) | MAPTNPC1RAB9ANPSR1TSHR | |
| SCHEMBL19083039 | 0.75 | KIF11 (0.38) | KMT2ACYP3A4CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL15871669 | 0.74 | GRM4 (0.38) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL4100127 | 0.72 | KDM4E (0.42) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL2950568 | 0.71 | HPGD (0.45) | KDM4ENPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL12087389 | 0.70 | KDM4E (0.57) | KDM4EMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580402-B2 | Dibenzothiophene-containing materials in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-8288543-B2 | Emissive transition-metal complexes with both carbon-phosphorus ancillary and chromophoric chelates, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-16 | — | — | US | disclosed |
| US-8288543-B2 | Emissive transition-metal complexes with both carbon-phosphorus ancillary and chromophoric chelates, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-16 | — | — | US | disclosed |
| US-20120012829-A1 | DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES | UNIVERSAL DISPLAY CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
| US-7923521-B2 | Process for preparing ortho-metallated metal compounds | MERCK PATENT GMBH (DE) | 2011-04-12 | — | — | US | disclosed |
| US-7923521-B2 | Process for preparing ortho-metallated metal compounds | MERCK PATENT GMBH (DE) | 2011-04-12 | — | — | US | disclosed |
| EP-1957505-B1 | PROCESS FOR PREPARING ORTHO-METALLATED METAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-7759490-B2 | Phosphorescent Osmium (II) complexes and uses thereof | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-07-20 | — | — | US | disclosed |
| US-20090209756-A1 | Emissive transition-metal complexes with both carbon-phosphorus ancillary and chromophoric chelates, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2009-08-20 | — | — | US | disclosed |
| US-20090058281-A1 | organic light emitting diodes; plasma enchanced chemical vapor deposition; metal organic chemical vapor deposition | SAMSUNG DISPLAY CO., LTD. (KR) | 2009-03-05 | — | — | US | disclosed |
| US-20080312396-A1 | Process for Preparing Ortho-Metallated Metal Compounds | UDC IRELAND LIMITED (IE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312396-A1 | Process for Preparing Ortho-Metallated Metal Compounds | UDC IRELAND LIMITED (IE) | 2008-12-18 | — | — | US | disclosed |
| WO-2007065523-A1 | PROCESS FOR PREPARING ORTHO-METALLATED METAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
| US-20070001166-A1 | Phosphorescent Osmium (II) complexes and uses thereof | TAO YE | 2007-01-04 | — | — | US | disclosed |
| US-7002013-B1 | Pt complexes as phosphorescent emitters in the fabrication of organic light emitting diodes | NATIONAL TSING HUA UNIVERSITY (TW) | 2006-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312396-A1 | Process for Preparing Ortho-Metallated Metal Compounds | SOD1, NISCH, FHIT | KDM4E 2080/4885MAPT 317/4885NPC1 4529/4885 |
| US-20090209756-A1 | Emissive transition-metal complexes with both carbon-phosphorus ancillary and chromophoric chelates, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | ORC3, EML4, NCL | KDM4E 3491/4885MAPT 2070/4885NPC1 1377/4885 |
| US-20070001166-A1 | Phosphorescent Osmium (II) complexes and uses thereof | OCIAD2, OCIAD1, ORC3 | KDM4E 4048/4885MAPT 4394/4885NPC1 1222/4885 |
| US-20090058281-A1 | organic light emitting diodes; plasma enchanced chemical vapor deposition; metal organic chemical vapor deposition | SDC4, C9, SDC1 | KDM4E 2031/4885MAPT 3737/4885NPC1 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.