SCHEMBL29489378

SCHEMBL29489378

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)CC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ VIPR1 P32241 4/20 0.50
▸ VIPR2 P41587 6/20 0.48
▸ BACE1 P56817 1/20 0.48
▸ KISS1R Q969F8 2/20 0.48
▸ GRIN2D O15399 1/20 0.47
▸ GRIN3B O60391 1/20 0.47
▸ GRIN1 Q05586 1/20 0.47
▸ GRIN2A Q12879 1/20 0.47
▸ GRIN2B Q13224 1/20 0.47
▸ GRIN2C Q14957 1/20 0.47
▸ GRIN3A Q8TCU5 1/20 0.47
▸ TASP1 Q9H6P5 1/20 0.46
▸ TFPI P10646 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974502 0.90 KISS1R (0.48) VIPR1VIPR2BACE1KISS1RGRIN2D
SCHEMBL30712884 0.89 VIPR1 (0.57) VIPR1VIPR2BACE1GRIN2DGRIN3B
SCHEMBL31318575 0.89 VIPR1 (0.53) VIPR1VIPR2BACE1GRIN2DGRIN3B
SCHEMBL29965025 0.88 VIPR1 (0.56) VIPR1VIPR2BACE1GRIN2DGRIN3B
SCHEMBL30662325 0.88 VIPR1 (0.58) VIPR1VIPR2BACE1GRIN2DGRIN3B
SCHEMBL4515922 0.88 ENPEP (0.48) VIPR1VIPR2BACE1KISS1RGRIN2D
SCHEMBL4515920 0.88 ENPEP (0.48) VIPR1VIPR2BACE1KISS1RGRIN2D
SCHEMBL30182730 0.87 NPY4R (0.46) VIPR1TFPI
SCHEMBL29489382 0.87 GRIN2D (0.59) VIPR1VIPR2GRIN2DGRIN3BGRIN1
SCHEMBL30863950 0.87 TASP1 (0.49) VIPR1VIPR2BACE1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11291407-B2 Detection of high risk drusen APELLIS PHARMACEUTICALS, INC. (US) 2022-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291407-B2 Detection of high risk drusen EXOSC4, EXOSC5, EXOSC10 VIPR1 1035/4885VIPR2 1841/4885BACE1 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback