Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494547 | 0.73 | RAB9A (0.48) | SMN1; SMN2HTTBCHEBTKHPGD | |
| SCHEMBL29494503 | 0.72 | HDAC1 (0.44) | SMN1; SMN2HTTBCHENOTUMALDH1A1 | |
| SCHEMBL29494535 | 0.71 | KLKB1 (0.49) | SMN1; SMN2HPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL29494461 | 0.71 | BLK (0.50) | SMN1; SMN2HTTBCHEBTKHPGD | |
| SCHEMBL29494276 | 0.68 | MEN1 (0.62) | HPGDALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL29494480 | 0.68 | MEN1 (0.42) | SMN1; SMN2HTTBCHEALDH1A1RAB9A | |
| SCHEMBL29494509 | 0.67 | NOTUM (0.47) | NOTUMRAB9ANPC1KLKB1 | |
| SCHEMBL29494470 | 0.66 | METTL3 (0.43) | SMN1; SMN2HTTBCHEKLKB1MEN1 | |
| SCHEMBL24501603 | 0.64 | DRD4 (0.38) | RAB9ANPC1KLKB1MEN1KMT2A | |
| SCHEMBL29494447 | 0.63 | MAPT (0.50) | SMN1; SMN2HTTBCHEBTKHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |