Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954051 | 0.86 | DHFR (0.44) | ALDH1A1USP2MAPTGFERDHFR | |
| SCHEMBL30399128 | 0.83 | FYN (0.41) | MAPTGAAKDM4EDHFRHSP90AA1 | |
| SCHEMBL2952950 | 0.80 | DHFR (0.43) | TTKDHFRHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL2948890 | 0.78 | TTK (0.45) | TTKDHFRHSP90AA1HSP90AB1HTR7 | |
| SCHEMBL2953676 | 0.77 | EGFR (0.39) | DHFR | |
| SCHEMBL2946282 | 0.76 | CNR1 (0.36) | TTKDHFRHSP90AA1HSP90AB1 | |
| SCHEMBL3034636 | 0.74 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL2953119 | 0.74 | TTK (0.43) | TTK | |
| SCHEMBL2946049 | 0.74 | DHFR (0.42) | TTKALDH1A1USP2TDP1LMNA | |
| SCHEMBL2953492 | 0.73 | TTK (0.47) | TTKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |