Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399128 | 0.79 | FYN (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL13177798 | 0.79 | HTR4 (0.41) | KCNH2PIM1CCR1F10CDK1 | |
| SCHEMBL3034624 | 0.78 | PDE7A (0.41) | PIM1 | |
| SCHEMBL2952950 | 0.78 | DHFR (0.43) | HSP90AA1HSP90AB1INSRALK | |
| SCHEMBL2954051 | 0.78 | DHFR (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL2948890 | 0.77 | TTK (0.45) | HSP90AA1HSP90AB1INSRIGF1RALK | |
| SCHEMBL2953119 | 0.77 | TTK (0.43) | INSRIGF1RALK | |
| SCHEMBL2952077 | 0.76 | INSR (0.42) | HSP90AA1HSP90AB1INSRIGF1RALK | |
| SCHEMBL2950126 | 0.74 | TTK (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL2952940 | 0.74 | SMPD3 (0.41) | INSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |