SCHEMBL29504162

SCHEMBL29504162

COC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.45
MALT1 Q9UDY8 7/20 0.39
RBP4 P02753 1/20 0.39
ALDH1A1 P00352 1/20 0.38
F2 P00734 1/20 0.37
PLAU P00749 1/20 0.37
KLKB1 P03952 1/20 0.37
ELANE P08246 1/20 0.37
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.36
PKM P14618 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23249321 1.00 DHODH (0.45) DHODHMALT1RBP4ALDH1A1F2
SCHEMBL15289958 0.89 DHODH (0.42) DHODHMALT1RBP4
SCHEMBL28341915 0.89 DHODH (0.38) DHODHMALT1RBP4ALDH1A1
SCHEMBL384694 0.87 ALDH1A1 (0.45) MALT1RBP4ALDH1A1ALOX15HTT
SCHEMBL29372796 0.87 ALDH1A1 (0.47) DHODHALDH1A1POLB
SCHEMBL1762554 0.87 ALDH1A1 (0.47) DHODHALDH1A1POLB
SCHEMBL26906447 0.87 MAPT (0.44) DHODHALDH1A1ELANEPOLB
SCHEMBL28801877 0.86 DHODH (0.39) DHODHMALT1RBP4
SCHEMBL28824117 0.85 DHODH (0.39) DHODHMALT1
SCHEMBL44760 0.85 MALT1 (0.39) DHODHMALT1RBP4ALDH1A1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114641471-B Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2025-05-23 CN disclosed
CN-119039270-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2024-11-29 CN disclosed
CN-114650985-B Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2024-09-13 CN disclosed
CN-114650987-B Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2024-09-06 CN disclosed
CN-117105908-B Bisamide pesticide and application thereof 帕潘纳(北京)科技有限公司 2023-12-22 CN disclosed
CN-117105908-A Bisamide pesticide and application thereof 帕潘纳(北京)科技有限公司 2023-11-24 CN disclosed
EP-4045487-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2022-08-24 EP disclosed
US-20220259177-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC IP TECHNOLOGY GMBH (CH) 2022-08-18 US disclosed
CN-114650987-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-21 CN disclosed
CN-114650984-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-21 CN disclosed
CN-114650985-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-21 CN disclosed
CN-114641471-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-17 CN disclosed
CN-114555582-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-05-27 CN disclosed
EP-3976588-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2022-04-06 EP disclosed
EP-3976589-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2022-04-06 EP disclosed
EP-3976590-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2022-04-06 EP disclosed
EP-3976591-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC Corporation (US) 2022-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259177-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID KYAT3, PDXK, CBR3 DHODH 257/4885MALT1 3604/4885RBP4 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.