SCHEMBL44760

SCHEMBL44760

COC(=O)c1cc(N)nn1-c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 5/20 0.39
RBP4 P02753 1/20 0.39
F2 P00734 1/20 0.39
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.36
PKM P14618 1/20 0.36
CYP2C19 P33261 1/20 0.36
TRPA1 O75762 1/20 0.36
DHODH Q02127 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384694 0.87 ALDH1A1 (0.45) MALT1RBP4ALDH1A1SMN1; SMN2ALOX15
SCHEMBL13483399 0.87 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2HTTKDM4E
SCHEMBL45318 0.85 KMT2A (0.41) MALT1RBP4ALDH1A1
SCHEMBL23249321 0.85 DHODH (0.45) MALT1RBP4F2ALDH1A1ALOX15
SCHEMBL29504162 0.85 DHODH (0.45) MALT1RBP4F2ALDH1A1ALOX15
SCHEMBL591388 0.84 TRPA1 (0.41) MALT1ALDH1A1SMN1; SMN2TRPA1
SCHEMBL27766931 0.84 MALT1 (0.38) MALT1SMN1; SMN2PKMTRPA1
SCHEMBL421559 0.83 MALT1 (0.38) MALT1RBP4ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL45109 0.83 MALT1 (0.38) MALT1RBP4F2ALDH1A1ALOX15
SCHEMBL2623669 0.83 MALT1 (0.39) MALT1RBP4ALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
EP-2582688-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2013-04-24 EP disclosed
CN-103068813-A Anthranilic acid diamide derivatives BAYER CROPSCIENCE AG 2013-04-24 CN disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed
WO-2011157654-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 MALT1 4605/4885RBP4 3766/4885F2 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.