Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961094 | 0.75 | HTR6 (0.47) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL18986682 | 0.71 | RAB9A (0.46) | GAAMEN1KMT2AALDH1A1PKM | |
| SCHEMBL322928 | 0.69 | NOTUM (0.70) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL24282440 | 0.68 | PARL (0.50) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL21496871 | 0.68 | NOTUM (0.68) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL2124966 | 0.67 | NOTUM (0.60) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL6744239 | 0.66 | ALDH1A1 (0.71) | GAAKMT2ALMNAALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL28278641 | 0.66 | NOTUM (0.66) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL22231295 | 0.64 | KMT2A (0.46) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27513834 | 0.64 | HTR6 (0.83) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12157753-B2 | Process for preparing Fostemsavir | ViiV Healthcare UK (No.4) Limited (GB) | 2024-12-03 | — | — | US | disclosed |
| EP-3911651-B1 | PROCESS FOR PREPARING FOSTEMSAVIR | VIIV HEALTHCARE UK NO 4 LTD (GB) | 2024-01-10 | — | — | EP | disclosed |
| US-20220106341-A1 | PROCESS FOR PREPARING FOSTEMSAVIR | ViiV Healthcare UK (No.4) Limited (GB) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157753-B2 | Process for preparing Fostemsavir | FIP1L1, CYP3A4, SAMHD1 | GAA 957/4885MEN1 771/4885KMT2A 2720/4885 |
| US-20220106341-A1 | PROCESS FOR PREPARING FOSTEMSAVIR | FIP1L1, CYP3A4, SAMHD1 | GAA 957/4885MEN1 771/4885KMT2A 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.