Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29259654 | 0.86 | ALDH1A1 (0.51) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL29523397 | 0.84 | NUDT1 (0.57) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL1768671 | 0.84 | NUDT1 (0.57) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL27957250 | 0.82 | POLB (0.56) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL30313610 | 0.80 | TSHR (0.60) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL827693 | 0.79 | PSMD14 (0.57) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL22169485 | 0.79 | LMNA (0.44) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL13610182 | 0.77 | ALDH1A1 (0.62) | LMNAALDH1A1HPGDCYP3A4RXFP1 | |
| SCHEMBL227218 | 0.76 | NCF1 (0.47) | ALDH1A1HPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL28170674 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1HPGDCYP3A4RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |