Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610182 | 0.95 | ALDH1A1 (0.62) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL1768671 | 0.85 | NUDT1 (0.57) | TSHRL3MBTL1CYP3A4TP53KDM4E | |
| SCHEMBL29523397 | 0.85 | NUDT1 (0.57) | TSHRL3MBTL1CYP3A4TP53KDM4E | |
| SCHEMBL16859557 | 0.82 | TSHR (0.77) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL29671333 | 0.82 | TSHR (0.77) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL30604067 | 0.82 | ATM (0.69) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL29259654 | 0.81 | ALDH1A1 (0.51) | TDP1CYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL9200082 | 0.80 | HTR3E (0.62) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL30201809 | 0.80 | LMNA (0.50) | CYP3A4TP53KDM4EALDH1A1LMNA | |
| SCHEMBL31310820 | 0.80 | PLA2G2A (0.65) | TSHRL3MBTL1TDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867284-A | Heterocyclic compounds as trigger receptor 2 agonists expressed on myeloid cells and methods of use | 安进公司 | 2023-03-28 | — | — | CN | disclosed |