Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK3 | Q9Y572 | 10/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29525507 | 0.83 | RIPK1 (0.63) | RIPK3RIPK1RAB9AGAAALDH1A1 | |
| SCHEMBL14363136 | 0.80 | MAPK1 (0.62) | RAB9AGAAP2RX4ALDH1A1MAPK1 | |
| SCHEMBL29525913 | 0.79 | MAPT (0.61) | RIPK3RIPK1RAB9AMAPK1GFER | |
| SCHEMBL29525753 | 0.76 | MAPK14 (0.49) | RIPK3RIPK1GAAALDH1A1 | |
| SCHEMBL14363132 | 0.76 | RAB9A (0.57) | RAB9AGAAALDH1A1MAPK1POLB | |
| SCHEMBL15474249 | 0.75 | USP2 (0.70) | RAB9AGAAALDH1A1MAPK1POLB | |
| SCHEMBL2271181 | 0.74 | GAA (0.60) | RAB9AGAAALDH1A1 | |
| SCHEMBL27944444 | 0.74 | MEN1 (0.64) | RAB9AKCNQ2GAAALDH1A1POLB | |
| SCHEMBL19322286 | 0.73 | RAB9A (0.64) | RAB9AGAAALDH1A1MAPK1POLB | |
| SCHEMBL5696445 | 0.73 | ALDH1A1 (0.59) | KCNQ2GAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053630-B | Benzothiazole derivative and application thereof | 中国人民解放军第二军医大学 | 2022-04-01 | — | — | CN | claimed |
| CN-109053630-B | Benzothiazole derivative and application thereof | 中国人民解放军第二军医大学 | 2022-04-01 | — | — | CN | disclosed |