Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.63 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29525477 | 0.83 | RIPK3 (0.61) | RIPK1RIPK3ALDH1A1MAPK1GAA | |
| SCHEMBL31675008 | 0.82 | LMNA (0.77) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL27858328 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL28492957 | 0.77 | LMNA (0.52) | RIPK1RIPK3LMNAKMT2AMEN1 | |
| SCHEMBL31675010 | 0.77 | LMNA (0.77) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL826741 | 0.77 | RIPK1 (0.52) | RIPK1RIPK3LMNAKMT2AMEN1 | |
| SCHEMBL2271165 | 0.77 | KDM4E (0.62) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL10160140 | 0.76 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL826828 | 0.75 | BRAF (0.57) | RIPK1RIPK3LMNAKMT2AMEN1 | |
| SCHEMBL8801786 | 0.74 | L3MBTL1 (0.53) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053630-B | Benzothiazole derivative and application thereof | 中国人民解放军第二军医大学 | 2022-04-01 | — | — | CN | claimed |
| CN-109053630-B | Benzothiazole derivative and application thereof | 中国人民解放军第二军医大学 | 2022-04-01 | — | — | CN | disclosed |