Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 3/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093363 | 0.79 | PTGS2 (0.61) | PTGS2HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL5645566 | 0.73 | GPR84 (0.65) | HTR2AGPR84ALDH1A1DUSP3IMPDH2 | |
| SCHEMBL30958471 | 0.73 | GPR84 (0.65) | HTR2AGPR84ALDH1A1DUSP3IMPDH2 | |
| SCHEMBL18509666 | 0.73 | PTGS2 (0.57) | PTGS2GSK3BTP53 | |
| SCHEMBL20935248 | 0.72 | PTGS2 (0.56) | PTGS2GSK3BKDM4ETP53TSHR | |
| SCHEMBL18029055 | 0.70 | PTGS2 (0.53) | PTGS2HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL13036629 | 0.69 | DYRK1A (0.43) | PTGS2GSK3BKDM4EPRMT5 | |
| SCHEMBL7716799 | 0.67 | TRPA1 (0.45) | MAPTALDH1A1TP53 | |
| SCHEMBL31186853 | 0.67 | TRPA1 (0.45) | MAPTALDH1A1TP53 | |
| SCHEMBL28909080 | 0.66 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240091171-A1 | DERMATOLOGICAL COMPOSITIONS AND USES THEREOF | BABAPOUR REZA (US) | 2024-03-21 | — | — | US | disclosed |
| WO-2022082218-A1 | IMPROVED DERMATOLOGICAL COMPOSITIONS AND USES THEREOF | BABAPOUR REZA (US) | 2022-04-21 | — | — | WO | disclosed |