SCHEMBL29534865

SCHEMBL29534865

CC(=O)Nc1c(Cl)ccc(NC(=O)OC(C)(C)C)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.41
LCK P06239 4/20 0.41
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP17A1 P05093 1/20 0.37
CDC7 O00311 1/20 0.36
PLK4 O00444 1/20 0.36
DYRK3 O43781 1/20 0.36
JAK2 O60674 1/20 0.36
ROCK2 O75116 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
INSR P06213 1/20 0.36
CDK1 P06493 1/20 0.36
ROS1 P08922 1/20 0.36
PIM1 P11309 1/20 0.36
FGFR1 P11362 1/20 0.36
PRKACA P17612 1/20 0.36
FLT1 P17948 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19932178 0.78 CXCR2 (0.48) ATRLCKHSP90AA1HSP90AB1CYP17A1
SCHEMBL3784448 0.77 GPR35 (0.50) ATRLCKHSP90AA1HSP90AB1ALDH1A1
SCHEMBL28146075 0.76 MEN1 (0.60) LCKALDH1A1LMNAMEN1KMT2A
SCHEMBL19932183 0.75 TAS1R3 (0.42) ATRLCKHSP90AA1HSP90AB1ALDH1A1
SCHEMBL3790491 0.75 LCK (0.52) ATRLCKHSP90AA1HSP90AB1ALDH1A1
SCHEMBL3288639 0.75 CYP17A1 (0.44) ATRHSP90AA1HSP90AB1CYP17A1LMNA
SCHEMBL5423774 0.75 PDK1 (0.57) ATRLCKHSP90AA1HSP90AB1CYP17A1
SCHEMBL31488143 0.74 ATR (0.60) ATRLCKALDH1A1LMNAMEN1
SCHEMBL20670511 0.74 CYP17A1 (0.42) ATRLCKHSP90AA1HSP90AB1CYP17A1
SCHEMBL28738831 0.73 PDK1 (0.56) HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-07-17 US disclosed
US-11944099-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2024-04-02 US disclosed
EP-3971166-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2022-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11944099-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD ATR 1636/4885LCK 806/4885HSP90AA1 918/4885
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD ATR 1636/4885LCK 806/4885HSP90AA1 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.