SCHEMBL2954709

SCHEMBL2954709

O=S(=O)(Cl)c1ccc(C2CC2)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 2/20 0.40
TSHR P16473 3/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 2/20 0.34
TRPV4 Q9HBA0 2/20 0.32
MAPK1 P28482 1/20 0.31
HSD11B1 P28845 1/20 0.31
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925439 0.80 TRPV4 (0.47) WDR5LMNAHTTTRPV4HSD11B1
SCHEMBL2921647 0.79 PIK3C3 (0.37) WDR5TRPV4HSD11B1
SCHEMBL25318742 0.75 TRPV4 (0.58) TRPV4
SCHEMBL19682382 0.75 TRPV4 (0.39) WDR5TRPV4
SCHEMBL1814581 0.72 HSP90AA1 (0.43) TSHRLMNAHTTTRPV4MAPK1
SCHEMBL31470482 0.72 HSP90AA1 (0.43) TSHRLMNAHTTTRPV4MAPK1
SCHEMBL2746854 0.72 ACMSD (0.38) LMNAHTTACMSD
SCHEMBL16399374 0.72 ESR2 (0.37) WDR5ACMSD
SCHEMBL2837743 0.71 WDR5 (0.38) WDR5TSHRLMNAHPGDHTT
SCHEMBL3407211 0.71 CA1 (0.43) WDR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101878197-A Method for producing 3-mercaptoaniline compound IHARA CHEMICAL IND CO 2010-11-03 CN disclosed
EP-2226312-A1 METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2010-09-08 EP disclosed