Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548391 | 0.89 | SPR (0.40) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548473 | 0.89 | SPR (0.37) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548733 | 0.86 | RET (0.41) | SPRRET | |
| SCHEMBL29548305 | 0.80 | SPR (0.40) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548514 | 0.75 | GPR119 (0.44) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548575 | 0.73 | GPR119 (0.37) | SPRRORCMEN1KMT2A | |
| SCHEMBL29548540 | 0.72 | RET (0.39) | SPRRETSCD5 | |
| SCHEMBL26631332 | 0.70 | HDAC2 (0.40) | SPRACACBSCD5MEN1KMT2A | |
| SCHEMBL29426949 | 0.69 | HDAC2 (0.39) | ACACBRORCSCD5GPR183 | |
| SCHEMBL29024527 | 0.69 | HDAC2 (0.39) | ACACBRORCSCD5GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |