Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548391 | 0.89 | SPR (0.40) | SPRRETCYP11B2ACACBNPBWR1 | |
| SCHEMBL29548481 | 0.89 | SPR (0.37) | SPRRETCYP11B2POLBACACB | |
| SCHEMBL29548733 | 0.86 | RET (0.41) | SPRRETGPR119 | |
| SCHEMBL29548305 | 0.80 | SPR (0.40) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548575 | 0.75 | GPR119 (0.37) | SPRMAPTTP53LMNAMEN1 | |
| SCHEMBL29548514 | 0.75 | GPR119 (0.44) | SPRRETCYP11B2ACACBSCD5 | |
| SCHEMBL29548540 | 0.72 | RET (0.39) | SPRRETSCD5GPR119 | |
| SCHEMBL25412980 | 0.71 | PDE4B (0.49) | — | |
| SCHEMBL25757796 | 0.70 | DGAT1 (0.43) | POLBMAPTTP53NPBWR1MCHR1 | |
| SCHEMBL26631332 | 0.70 | HDAC2 (0.40) | SPRPOLBACACBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |