Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.40 |
| ▸ | RET | P07949 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487947 | 0.86 | MAPT (0.46) | RETGPR119 | |
| SCHEMBL29548514 | 0.86 | GPR119 (0.44) | SPRRETACACBSCD5EGLN2 | |
| SCHEMBL29548540 | 0.82 | RET (0.39) | SPRRETSCD5EGLN2GPR119 | |
| SCHEMBL29548391 | 0.81 | SPR (0.40) | SPRRETACACBSCD5CYP11B2 | |
| SCHEMBL29548481 | 0.80 | SPR (0.37) | SPRRETACACBSCD5CYP11B2 | |
| SCHEMBL29548473 | 0.80 | SPR (0.37) | SPRRETACACBSCD5CYP11B2 | |
| SCHEMBL29548733 | 0.80 | RET (0.41) | SPRRETEGLN2GPR119 | |
| SCHEMBL29548851 | 0.78 | SCD5 (0.38) | SPRRETSCD5CYP11B2GPR119 | |
| SCHEMBL31487838 | 0.74 | HTT (0.53) | GPR119 | |
| SCHEMBL26631332 | 0.72 | HDAC2 (0.40) | SPRACACBSCD5GPR183GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |