Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548391 | 0.87 | SPR (0.40) | RETSPR | |
| SCHEMBL29548481 | 0.86 | SPR (0.37) | RETSPR | |
| SCHEMBL29548473 | 0.86 | SPR (0.37) | RETGPR119SPR | |
| SCHEMBL29548305 | 0.80 | SPR (0.40) | RETGPR119EGLN2SPR | |
| SCHEMBL29548514 | 0.74 | GPR119 (0.44) | RETGPR119EGLN2SPR | |
| SCHEMBL29548540 | 0.71 | RET (0.39) | RETGPR119EGLN2SPR | |
| SCHEMBL29548575 | 0.71 | GPR119 (0.37) | GPR119SPR | |
| SCHEMBL26631332 | 0.68 | HDAC2 (0.40) | GPR119SPR | |
| SCHEMBL25031301 | 0.67 | HPGD (0.41) | GPR119 | |
| SCHEMBL25412980 | 0.67 | PDE4B (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |