Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 11/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548514 | 0.84 | GPR119 (0.44) | RETHDAC1HDAC2SPRGPR119 | |
| SCHEMBL29548305 | 0.82 | SPR (0.40) | RETSPRGPR119SCD5EGLN2 | |
| SCHEMBL29548851 | 0.76 | SCD5 (0.38) | RETHDAC1HDAC2SPRGPR119 | |
| SCHEMBL29548156 | 0.75 | — | — | |
| SCHEMBL29548391 | 0.72 | SPR (0.40) | RETSPRSCD5 | |
| SCHEMBL29548473 | 0.72 | SPR (0.37) | RETSPRGPR119SCD5 | |
| SCHEMBL29548481 | 0.72 | SPR (0.37) | RETSPRSCD5 | |
| SCHEMBL25603496 | 0.71 | NAMPT (0.44) | HDAC1HDAC2GPR119SCD5 | |
| SCHEMBL29548733 | 0.71 | RET (0.41) | RETSPRGPR119EGLN2 | |
| SCHEMBL31487947 | 0.69 | MAPT (0.46) | RETGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |