Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29552235 | 0.84 | TACR1 (0.36) | L3MBTL1PDE7ASYKPTGS2PIK3CA | |
| SCHEMBL29552160 | 0.83 | L3MBTL1 (0.46) | L3MBTL1PDE7AEGFRSYKSLC6A2 | |
| SCHEMBL29551761 | 0.74 | TYK2 (0.57) | L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL29922678 | 0.73 | L3MBTL1 (0.42) | L3MBTL1PDE7AEGFRSYKSLC6A2 | |
| SCHEMBL28362527 | 0.73 | L3MBTL1 (0.42) | L3MBTL1PDE7AEGFRSYKSLC6A2 | |
| SCHEMBL29552554 | 0.72 | HTR2C (0.40) | ADRA2AADRA2BADRA2CALDH1A1CDK4 | |
| SCHEMBL23486417 | 0.71 | FABP4 (0.46) | PTGS2GFERHPGDALDH1A1 | |
| SCHEMBL22609254 | 0.70 | DHODH (0.46) | EGFRPTGS2ALDH1A1CDK9 | |
| SCHEMBL29552335 | 0.68 | PTGS2 (0.37) | PDE7ASYKPTGS2 | |
| SCHEMBL3557930 | 0.67 | SLC6A2 (0.45) | L3MBTL1SLC6A2SLC6A4ACVR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |