Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952277 | 0.77 | MAP4K4 (0.45) | CDK1CCNB1CCNE1CDK2ATR | |
| SCHEMBL2956345 | 0.71 | PDE4B (0.42) | CDK1CDK2PI4KB | |
| SCHEMBL2953676 | 0.69 | EGFR (0.39) | DHFRHRH4 | |
| SCHEMBL2951209 | 0.68 | KDM4E (0.42) | CDK1CCNB1CCNE1CDK2SMN1; SMN2 | |
| SCHEMBL29015726 | 0.68 | PI4KA (0.36) | CDK1CCNB1CCNE1CDK2ALDH1A1 | |
| SCHEMBL2948868 | 0.68 | CYP1A2 (0.53) | CDK1CCNB1CCNE1CDK2SMN1; SMN2 | |
| SCHEMBL2946285 | 0.67 | PDE4B (0.46) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2946282 | 0.67 | CNR1 (0.36) | CDK1CCNB1CCNE1CDK2DHFR | |
| SCHEMBL26608024 | 0.66 | ALDH1A1 (0.50) | CTSSALDH1A1SMN1; SMN2TLR7NPSR1 | |
| SCHEMBL2946551 | 0.66 | CDK1 (0.41) | CDK1CCNB1CCNE1CDK2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |