Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561528 | 0.89 | MAPT (0.54) | MAPTCYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL29561462 | 0.86 | RELA (0.58) | MAPTCYP19A1MEN1KMT2ALMNA | |
| SCHEMBL29562518 | 0.84 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29562355 | 0.84 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29562105 | 0.80 | MAPT (0.61) | MAPTCYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL14048137 | 0.80 | KMT2A (0.57) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29561797 | 0.79 | MAPT (0.61) | MAPTALDH1A1LMNAPGRPKM | |
| SCHEMBL29562498 | 0.78 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18546034 | 0.78 | CYP19A1 (0.73) | CYP19A1ALDH1A1MEN1KMT2AALPL | |
| SCHEMBL29562114 | 0.77 | MAPT (0.66) | MAPTCYP19A1ALDH1A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |