SCHEMBL2956233

SCHEMBL2956233

COc1ccc(S(OS(=O)(=O)c2ccccc2F)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.45
PKLR P30613 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
NFE2L2 Q16236 2/20 0.42
MMP2 P08253 2/20 0.42
MMP8 P22894 2/20 0.42
MMP12 P39900 2/20 0.42
MMP13 P45452 2/20 0.42
MMP14 P50281 2/20 0.42
MMP16 P51512 2/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2957979 0.97 MMP13 (0.43) PKMPKLRSMN1; SMN2LMNAHTT
SCHEMBL2966033 0.84 HSD11B1 (0.42) SMN1; SMN2HTTL3MBTL1ALDH1A1NFE2L2
SCHEMBL2957840 0.84 KMT2A (0.44) ALDH1A1NFE2L2KMT2AGAAMEN1
SCHEMBL2956300 0.84 CNR1 (0.41) PKMSMN1; SMN2LMNAHTTTDP1
SCHEMBL2954352 0.82 FFAR4 (0.43) PKMSMN1; SMN2LMNAHTTTDP1
SCHEMBL2960439 0.82 HTT (0.41) SMN1; SMN2HTTTDP1L3MBTL1ALDH1A1
SCHEMBL450234 0.81 KMT2A (0.54) PKMSMN1; SMN2LMNAHTTTDP1
SCHEMBL3183368 0.79 GAA (0.52) LMNAMMP2MMP8MMP12MMP13
SCHEMBL450431 0.79 HTT (0.53) PKMSMN1; SMN2LMNAHTTTDP1
SCHEMBL2964762 0.79 HTT (0.53) PKMSMN1; SMN2LMNAHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759045-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-20 US disclosed
US-20090004601-A1 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-6893794-B2 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-17 US disclosed
US-20040018445-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-01-29 US disclosed
US-20030068573-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-10 US disclosed