SCHEMBL2957979

SCHEMBL2957979

COc1ccc(S(OS(=O)(=O)c2ccccc2F)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 6/20 0.43
MMP2 P08253 5/20 0.43
MMP8 P22894 5/20 0.43
MMP12 P39900 5/20 0.43
MMP14 P50281 5/20 0.43
MMP16 P51512 5/20 0.43
PKM P14618 2/20 0.43
KMT2A Q03164 2/20 0.43
PKLR P30613 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2956233 0.97 PKM (0.45) MMP13MMP2MMP8MMP12MMP14
SCHEMBL2957840 0.88 KMT2A (0.44) KMT2AMEN1NPC1RAB9ASENP8
SCHEMBL2956300 0.87 CNR1 (0.41) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL2960439 0.85 HTT (0.41) KMT2AMEN1NPC1RAB9ASENP8
SCHEMBL450431 0.83 HTT (0.53) MMP13MMP2MMP8PKMSMN1; SMN2
SCHEMBL5169176 0.83 HTT (0.53) MMP13MMP2MMP8PKMSMN1; SMN2
SCHEMBL2964762 0.83 HTT (0.53) MMP13MMP2MMP8PKMSMN1; SMN2
SCHEMBL2958287 0.82 STAT3 (0.48) MMP13PKMSMN1; SMN2LMNAHTT
SCHEMBL3183368 0.82 GAA (0.52) MMP13MMP2MMP8MMP12MMP14
SCHEMBL2966033 0.82 HSD11B1 (0.42) KMT2AMEN1NPC1RAB9ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759045-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-20 US disclosed
US-20090004601-A1 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-6893794-B2 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-17 US disclosed
US-20040018445-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-01-29 US disclosed
US-20030068573-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-10 US disclosed