Avocadyne

Avocadyne

SCHEMBL29564402

C#CCCCCCCCCCCCC(O)CC(O)CO.C=CCCCCCCCCCCCC(O)CC(O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 6/20 1.00
CYP3A4 P08684 4/20 0.76
SMN1; SMN2 Q16637 3/20 0.76
MAPT P10636 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Avocadene SCHEMBL1051284 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadene SCHEMBL15944388 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadyne SCHEMBL18730915 0.87 USP2 (1.00) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
SCHEMBL31619136 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadyne SCHEMBL1970908 0.87 USP2 (1.00) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
SCHEMBL30697474 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadene SCHEMBL15191342 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
SCHEMBL31619135 0.87 USP2 (0.76) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadyne Acetate SCHEMBL25216029 0.79 USP2 (1.00) USP2CYP3A4SMN1; SMN2MAPTALDH1A1
Avocadyne SCHEMBL30697473 0.78 USP2 (0.81) USP2CYP3A4SMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390423-B2 Avocatin B for the treatment of diseases and conditions SP NUTRACEUTICALS INC. (CA) 2025-08-19 US claimed
EP-3976197-B1 THERAPEUTICS AND METHODS FOR PREDICTING AND OVERCOMING ENDOCRINE RESISTANCE IN BREAST CANCER LUNELLA BIOTECH INC (CA) 2025-07-16 EP claimed
US-11672810-B2 Therapeutics and methods for predicting and overcoming endocrine resistance in breast cancer LUNELLA BIOTECH, INC. (CA) 2023-06-13 US claimed
US-20230140688-A1 AVOCATIN B FOR THE TREATMENT OF DISEASES AND CONDITIONS SP NUTRACEUTICALS INC. (CA) 2023-05-04 US claimed
US-20220202836-A1 THERAPEUTICS AND METHODS FOR PREDICTING AND OVERCOMING ENDOCRINE RESISTANCE IN BREAST CANCER LUNELLA BIOTECH, INC. (CA) 2022-06-30 US claimed
EP-3976197-A1 THERAPEUTICS AND METHODS FOR PREDICTING AND OVERCOMING ENDOCRINE RESISTANCE IN BREAST CANCER Lunella Biotech, Inc. (CA) 2022-04-06 EP claimed
US-12553092-B2 Energetic cancer stem cells (E-CSCS): a new hyper-metabolic and proliferative tumor cell phenotype, driven by mitochondrial energy LUNELLA BIOTECH, INC. (CA) 2026-02-17 US disclosed
EP-4620479-A1 POSTBIOTIC PREPARATION COMPRISING PEDIOCOCCUS ACIDILACTICI FOR PREVENTING OR TREATING OBESITY Genbioma Aplicaciones, S.L. (ES) 2025-09-24 EP disclosed
US-12390423-B2 Avocatin B for the treatment of diseases and conditions SP NUTRACEUTICALS INC. (CA) 2025-08-19 US disclosed
US-12390423-B2 Avocatin B for the treatment of diseases and conditions SP NUTRACEUTICALS INC. (CA) 2025-08-19 US disclosed
US-12390423-B2 Avocatin B for the treatment of diseases and conditions SP NUTRACEUTICALS INC. (CA) 2025-08-19 US disclosed
EP-3976197-B1 THERAPEUTICS AND METHODS FOR PREDICTING AND OVERCOMING ENDOCRINE RESISTANCE IN BREAST CANCER LUNELLA BIOTECH INC (CA) 2025-07-16 EP disclosed
US-20250114413-A1 SYNBIOTIC SUPPLEMENT FORMULATION MEDISYN BIO INC (US) 2025-04-10 US disclosed
US-20230140688-A1 AVOCATIN B FOR THE TREATMENT OF DISEASES AND CONDITIONS SP NUTRACEUTICALS INC. (CA) 2023-05-04 US disclosed
EP-4168006-A1 NEW STRATEGY FOR TREATING PANCREATIC CANCER Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2023-04-26 EP disclosed
US-20230040965-A1 ENERGETIC CANCER STEM CELLS (E-CSCS): A NEW HYPER-METABOLIC AND PROLIFERATIVE TUMOR CELL PHENOTYPE, DRIVEN BY MITOCHONDRIAL ENERGY LUNELLA BIOTECH, INC. (CA) 2023-02-09 US disclosed
US-20230038352-A1 PROBIOTICS FOR REGULATING BLOOD GLUCOSE GENBIOMA APLICACIONES, S.L. (ES) 2023-02-09 US disclosed
US-11497759-B2 Repurposcins: targeted inhibitors of mitochondrial biogenesis for eradicating cancer stem cells LUNELLA BIOTECH, INC. (CA) 2022-11-15 US disclosed
EP-4076484-A1 PROBIOTICS FOR REGULATING BLOOD GLUCOSE Genbioma Aplicaciones, S.L. (ES) 2022-10-26 EP disclosed
US-11441195-B2 Energetic cancer stem cells (e-CSCs): a new hyper-metabolic and proliferative tumor cell phenotype, driven by mitochondrial energy LUNELLA BIOTECH, INC. (CA) 2022-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11672810-B2 Therapeutics and methods for predicting and overcoming endocrine resistance in breast cancer CYP27B1, TFAM, FIS1 USP2 1052/4885CYP3A4 1140/4885SMN1; SMN2 1917/4885
US-12553092-B2 Energetic cancer stem cells (E-CSCS): a new hyper-metabolic and proliferative tumor cell phenotype, driven by mitochondrial energy TXNRD2, TXNRD1, TXN2 USP2 1958/4885CYP3A4 2368/4885SMN1; SMN2 3477/4885
US-11441195-B2 Energetic cancer stem cells (e-CSCs): a new hyper-metabolic and proliferative tumor cell phenotype, driven by mitochondrial energy ALDH2, ALDH5A1, ECHS1 USP2 2037/4885CYP3A4 2819/4885SMN1; SMN2 4190/4885
US-20230040965-A1 ENERGETIC CANCER STEM CELLS (E-CSCS): A NEW HYPER-METABOLIC AND PROLIFERATIVE TUMOR CELL PHENOTYPE, DRIVEN BY MITOCHONDRIAL ENERGY ALDH2, ECHS1, ALDH5A1 USP2 1643/4885CYP3A4 3506/4885SMN1; SMN2 4459/4885
US-20220202836-A1 THERAPEUTICS AND METHODS FOR PREDICTING AND OVERCOMING ENDOCRINE RESISTANCE IN BREAST CANCER CYP27B1, TFAM, FIS1 USP2 1052/4885CYP3A4 1140/4885SMN1; SMN2 1917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.