Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | SLC37A4 | O43826 | 5/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955404 | 0.89 | BCL2 (0.47) | MEN1KMT2AALDH1A1MAPTELANE | |
| Aloesaponarin I SCHEMBL13317456 | 0.86 | ITGA2 (0.57) | MEN1KMT2AALDH1A1MAPTTSHR | |
| Aloesaponarin I SCHEMBL29657074 | 0.86 | ITGA2 (0.57) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL8952406 | 0.84 | SLC37A4 (0.58) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL5142787 | 0.82 | SLC37A4 (0.67) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL30848230 | 0.82 | SLC37A4 (0.67) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL4455117 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL23724050 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL2958068 | 0.79 | ELANE (0.49) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL14335022 | 0.77 | MEN1 (0.69) | MEN1KMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763740-B2 | Method for the production of mumbaistatin derivatives | SANOFI-AVENTIS (FR) | 2010-07-27 | — | — | US | disclosed |
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | MMAB, MLYCD, HMBS | MEN1 5/4885KMT2A 924/4885ALDH1A1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.