Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | PKLR | P30613 | 6/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 3/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957879 | 0.89 | MEN1 (0.52) | MAPTALDH1A1THRBTTRELANE | |
| SCHEMBL2957671 | 0.85 | MAPT (0.44) | MAPTLCKALDH1A1GLATHRB | |
| SCHEMBL4460906 | 0.80 | BCL2 (0.44) | BCL2MCL1MAPTLCKALDH1A1 | |
| SCHEMBL23724050 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1THRBTTRELANE | |
| SCHEMBL2958068 | 0.74 | ELANE (0.49) | MAPTALDH1A1TTRMITFELANE | |
| Aloesaponarin I SCHEMBL29657074 | 0.74 | ITGA2 (0.57) | MAPTALDH1A1THRBTTRELANE | |
| Aloesaponarin I SCHEMBL13317456 | 0.74 | ITGA2 (0.57) | MAPTALDH1A1THRBTTRELANE | |
| SCHEMBL3174840 | 0.74 | BCL2 (0.71) | BCL2MCL1MAPTLCKALDH1A1 | |
| SCHEMBL8976457 | 0.72 | MAPT (0.55) | MAPTALDH1A1THRBMITFMEN1 | |
| SCHEMBL23198952 | 0.72 | MAPT (0.61) | BCL2MCL1MAPTLCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763740-B2 | Method for the production of mumbaistatin derivatives | SANOFI-AVENTIS (FR) | 2010-07-27 | — | — | US | disclosed |
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | MMAB, MLYCD, HMBS | BCL2 1218/4885MCL1 58/4885MAPT 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.