Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020960 | 0.88 | ALDH1A1 (0.31) | LMNATSHRATP1A1ATP1B1ATP1A3 | |
| SCHEMBL11027439 | 0.78 | ALDH1A1 (0.32) | LMNATSHRATP1A1ATP1B1ATP1A3 | |
| SCHEMBL13969898 | 0.74 | TSHR (0.32) | TSHRATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL12611336 | 0.73 | — | — | |
| Hydrogen Peroxide SCHEMBL17420816 | 0.73 | LMNA (0.33) | LMNATSHRATP1A1ATP1B1ATP1A3 | |
| SCHEMBL3883605 | 0.71 | SLC6A2 (0.31) | — | |
| SCHEMBL31623102 | 0.71 | SLC6A2 (0.31) | — | |
| SCHEMBL2895674 | 0.71 | SLC6A2 (0.31) | — | |
| SCHEMBL9751398 | 0.71 | SLC6A2 (0.31) | — | |
| SCHEMBL7107643 | 0.70 | ATP1A1 (0.32) | LMNATSHRATP1A1ATP1B1ATP1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391790-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | TARO PHARMACEUTICALS INC. (CA) | 2023-12-07 | — | — | US | disclosed |
| US-11773108-B2 | Indene derivatives useful in treating pain and inflammation | TARO PHARMACEUTICALS INC. (CA) | 2023-10-03 | — | — | US | disclosed |
| US-20220306645-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | TARO PHARMACEUTICALS INC. (CA) | 2022-09-29 | — | — | US | disclosed |
| US-11352367-B2 | Indene derivatives useful in treating pain and inflammation | TARO PHARMACEUTICALS INC. (CA) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391790-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | IL1B, IL1A, LTB4R | LMNA 1993/4885TSHR 2588/4885ATP1A1 2362/4885 |
| US-20220306645-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | IL1B, IL1A, LTB4R | LMNA 2184/4885TSHR 2622/4885ATP1A1 2285/4885 |
| US-11352367-B2 | Indene derivatives useful in treating pain and inflammation | IL1B, IL1A, LTB4R | LMNA 1993/4885TSHR 2588/4885ATP1A1 2362/4885 |
| US-11773108-B2 | Indene derivatives useful in treating pain and inflammation | IL1B, IL1A, LTB4R | LMNA 2184/4885TSHR 2622/4885ATP1A1 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.