SCHEMBL29587902

SCHEMBL29587902

Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3cc(F)cc(F)c3)CCCC2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SCARB1 Q8WTV0 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4200829 0.75 SCARB1 (0.62) SCARB1
SCHEMBL4029839 0.66 SCARB1 (0.67) SCARB1
SCHEMBL13478790 0.64 SCARB1 (0.47) SCARB1
SCHEMBL13746591 0.63 SCARB1 (0.52) SCARB1
SCHEMBL13746604 0.62 SCARB1 (0.62) SCARB1
SCHEMBL26581388 0.62 ACHE (0.46) SCARB1
SCHEMBL4200388 0.61 SCARB1 (0.73) SCARB1
SCHEMBL4200984 0.61 SCARB1 (0.68) SCARB1
SCHEMBL13747782 0.61 SCARB1 (0.66) SCARB1
SCHEMBL7467529 0.60 HTR6 (0.47) SCARB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383558-B2 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections EMORY UNIVERSITY (US) 2025-08-12 — — US disclosed
EP-4556010-A2 JAK INHIBITORS FOR USE IN THE PREVENTION OR TREATMENT OF A VIRAL DISEASE CAUSED BY A CORONAVIRIDAE Emory University (US) 2025-05-21 — — EP disclosed
US-20250057837-A1 Methods for Treating HCV ABBVIE INC. (US) 2025-02-20 — — US disclosed
EP-2970357-B1 AMINO ACID PHOSPHORAMIDATE PRONUCLEOTIDES OF 2'-CYANO, AZIDO AND AMINO NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2025-01-01 — — EP disclosed
US-20240232171-A1 Methods for Treating HCV ABBVIE INC. (US) 2024-07-11 — — US disclosed
CN-107898790-B Antiviral JAK inhibitors for the treatment or prevention of retroviral and other viral infections 埃默里大学 2024-06-21 — — CN disclosed
US-20240173322-A1 ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS UNIV EMORY (US) 2024-05-30 — — US disclosed
US-20240115650-A1 Methods for Treating HCV ABBVIE INC. (US) 2024-04-11 — — US disclosed
US-20240082245-A1 Methods for Treating HCV ABBVIE INC (US) 2024-03-14 — — US disclosed
US-20230385268-A1 Methods for Treating HCV ABBVIE INC. (US) 2023-11-30 — — US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 — — US disclosed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 — — EP disclosed
EP-4159795-A1 THERAPEUTIC CONJUGATES WITH SULFATED DENDRIMERS FOR INTRACELLULAR TARGETING ICD-Therapeutics GmbH (DE) 2023-04-05 — — EP disclosed
US-11484534-B2 Methods for treating HCV ABBVIE INC. (US) 2022-11-01 — — US disclosed
US-20220288153-A1 Methods for Treating HCV ABBVIE INC. (US) 2022-09-15 — — US disclosed
US-20220110939-A1 ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS UNIV EMORY (US) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288153-A1 Methods for Treating HCV EIF2AK2, IFNAR1, IFNG SCARB1 273/4885
US-20250057837-A1 Methods for Treating HCV EIF2AK2, IFNAR1, IFNG SCARB1 240/4885
US-20240115650-A1 Methods for Treating HCV EIF2AK2, IFNAR1, IFNG SCARB1 240/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS SCARB1 1274/4885
US-20220110939-A1 ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS JAK1, JAK3, PNP SCARB1 3254/4885
US-11484534-B2 Methods for treating HCV EIF2AK2, IFNAR1, IFNG SCARB1 240/4885
US-20240082245-A1 Methods for Treating HCV EIF2AK2, IFNAR1, IFNG SCARB1 240/4885
US-20240173322-A1 ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS JAK1, JAK3, PNP SCARB1 4470/4885
US-12383558-B2 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections JAK1, JAK3, PNP SCARB1 4470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback