Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 8/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748808 | 1.00 | PKM (0.43) | PKMKCNMA1PDE2APDE10AGRM2 | |
| SCHEMBL29475370 | 0.96 | PKM (0.41) | PKMKCNMA1PDE2APDE10AGRM2 | |
| SCHEMBL29475401 | 0.96 | PKM (0.41) | PKMKCNMA1PDE2APDE10AGRM2 | |
| SCHEMBL19848305 | 0.76 | KCNMA1 (0.49) | PKMKCNMA1PDE2APDE10AMAPT | |
| SCHEMBL16858668 | 0.76 | PKM (0.41) | PKMKCNMA1PDE2APDE10AGRM2 | |
| SCHEMBL3893181 | 0.76 | DGAT1 (0.57) | KCNMA1MAPTKDM4EMAPK1HTT | |
| SCHEMBL21073734 | 0.74 | DGAT1 (0.51) | KCNMA1MAPTKDM4EMAPK1HTT | |
| SCHEMBL21904738 | 0.74 | DGAT1 (0.51) | KCNMA1MAPTKDM4ELMNAMAPK1 | |
| SCHEMBL1971917 | 0.74 | DGAT1 (0.51) | KCNMA1MAPTKDM4ELMNAMAPK1 | |
| SCHEMBL19915683 | 0.73 | KCNMA1 (0.49) | PKMKCNMA1GRM2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |