Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 11/20 | 0.47 |
| ▸ | MGAM | O43451 | 10/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.47 |
| ▸ | SI | P14410 | 10/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21073734 | 0.94 | DGAT1 (0.51) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL21904738 | 0.94 | DGAT1 (0.51) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1971917 | 0.94 | DGAT1 (0.51) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL21904737 | 0.92 | DGAT1 (0.49) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2732055 | 0.83 | DGAT1 (0.49) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29031460 | 0.83 | DGAT1 (0.49) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29354525 | 0.77 | TUBB4A (0.44) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL12019911 | 0.77 | TUBB4A (0.44) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1277493 | 0.77 | TUBB4A (0.44) | DGAT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL425007 | 0.77 | KMT2A (0.61) | DGAT1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141692-A1 | SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM | KORANEX CAPITAL (CA) | 2023-08-03 | — | — | WO | claimed |
| US-11708341-B2 | Synthesis of (S)-2-amino-4-methyl-((R)-2-methyloxirane-2-yl)-pentan-1-one and pharmaceutically acceptable salts thereof | AMGEN INC. | 2023-07-25 | — | — | US | claimed |
| EP-3494108-B1 | SYNTHESIS OF (S)-2-AMINO-4-METHYL-1-((R)-2-METHYLOXIRANE-2-YL)-PENTAN-1-ONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | AMGEN INC (US) | 2020-10-28 | — | — | EP | claimed |
| CN-114599375-B | Nucleic acid delivery promoters | 国立大学法人高知大学 | 2025-02-11 | — | — | CN | disclosed |
| EP-3899532-B1 | A LABELLING METHOD TO DISTINGUISH ISOBARIC AMINO ACIDS AND AMINO ACID COMBINATIONS | RAPID NOVOR INC (CA) | 2024-02-14 | — | — | EP | disclosed |
| WO-2023141692-A1 | SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM | KORANEX CAPITAL (CA) | 2023-08-03 | — | — | WO | disclosed |
| US-11708341-B2 | Synthesis of (S)-2-amino-4-methyl-((R)-2-methyloxirane-2-yl)-pentan-1-one and pharmaceutically acceptable salts thereof | AMGEN INC. | 2023-07-25 | — | — | US | disclosed |
| EP-3899532-A1 | A LABELLING METHOD TO DISTINGUISH ISOBARIC AMINO ACIDS AND AMINO ACID COMBINATIONS | Rapid Novor Inc. (CA) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020124252-A1 | A LABELLING METHOD TO DISTINGUISH ISOBARIC AMINO ACIDS AND AMINO ACID COMBINATIONS | RAPID NOVOR INC. (CA) | 2020-06-25 | — | — | WO | disclosed |
| EP-3380455-A1 | TRYPANOSOMES INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2018-10-03 | — | — | EP | disclosed |
| CN-108368152-A | Improvement in Solid phase peptide synthesis | CEM有限公司 | 2018-08-03 | — | — | CN | disclosed |
| WO-2014001820-A1 | JAPANESE CEDAR PEPTIDE FOR PREVENTING OR TREATING ALLERGY | CIRCASSIA LIMITED (GB) | 2014-01-03 | — | — | WO | disclosed |
| WO-2013179044-A2 | CLADOSPORIUM PEPTIDES | CIRCASSIA LIMITED (GB) | 2013-12-05 | — | — | WO | disclosed |
| WO-2013179043-A1 | ALTERNARIA PEPTIDES | CIRCASSIA LIMITED (GB) | 2013-12-05 | — | — | WO | disclosed |
| US-20090182057-A1 | DEUTERATED AMINOGLYCIDAL COMPOUNDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-07-16 | — | — | US | disclosed |
| EP-1487484-B1 | USE OF MIXTURES OF LIPOPEPTIDES FOR VACCINE PRODUCTION | CENTRE NAT RECH SCIENT (FR) | 2009-02-11 | — | — | EP | disclosed |
| EP-1801086-A1 | Synthesis of carbon acid amides | Synthacon GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |
| EP-1315739-B1 | METHOD FOR BINDING, IN SOLUTION, A PEPTIDE AND A LIPOPHILIC VECTOR AND USES THEREOF | PASTEUR INSTITUT (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1315739-A2 | METHOD FOR BINDING, IN SOLUTION, A PEPTIDE AND A LIPOPHILIC VECTOR AND USES THEREOF | INSTITUT PASTEUR DE LILLE Etablissement Public (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020558-A2 | METHOD FOR BINDING, IN SOLUTION, A PEPTIDE AND A LIPOPHILIC VECTOR AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182057-A1 | DEUTERATED AMINOGLYCIDAL COMPOUNDS | ADRB2, GLRB, ADRB1 | DGAT1 2172/4885KMT2A 3732/4885MAPT 3578/4885 |
| US-11708341-B2 | Synthesis of (S)-2-amino-4-methyl-((R)-2-methyloxirane-2-yl)-pentan-1-one and pharmaceutically acceptable salts thereof | EPOR, KDM5A, PSMA5 | DGAT1 4706/4885KMT2A 98/4885MAPT 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.