SCHEMBL1971917

SCHEMBL1971917

CN(C)C(n1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.51
▸ KMT2A Q03164 4/20 0.47
▸ MAPT P10636 2/20 0.47
▸ HTT P42858 2/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ KCNMA1 Q12791 1/20 0.43
▸ GAA P10253 11/20 0.43
▸ MGAM O43451 10/20 0.43
▸ AMY1A P0DUB6 10/20 0.43
▸ SI P14410 10/20 0.43
▸ MGAM2 Q2M2H8 10/20 0.43
▸ F2 P00734 2/20 0.43
▸ SLC9A1 P19634 2/20 0.43
▸ HPGD P15428 1/20 0.43
▸ KCNN4 O15554 1/20 0.43
▸ F12 P00748 3/20 0.43
▸ MIF P14174 1/20 0.43
▸ TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21904738 1.00 DGAT1 (0.51) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL3893181 0.94 DGAT1 (0.57) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL21073734 0.91 DGAT1 (0.51) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL21904737 0.89 DGAT1 (0.49) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL29031460 0.89 DGAT1 (0.49) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL2732055 0.89 DGAT1 (0.49) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL29803806 0.80 TUBB4A (0.41) KMT2A
SCHEMBL29874491 0.80 TUBB4A (0.41) DGAT1KMT2AMAPTHTTNPSR1
SCHEMBL29475370 0.79 PKM (0.41) KMT2AMAPTHTTKDM4EKCNMA1
SCHEMBL30495312 0.77 DGAT1 (0.47) DGAT1KMT2AMAPTHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2025-05-01 — — US claimed
WO-2023141693-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
WO-2023141692-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-20260124177-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR NOVITA PHARMACEUTICALS, INC. (US) 2026-05-07 — — US disclosed
EP-4096662-B1 PROCESS FOR PREPARATION OF LASMIDITAN ALIVUS LIFE SCIENCES LTD (IN) 2026-03-25 — — EP disclosed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-12508245-B2 Co-therapies including a metastasis inhibitor NOVITA PHARMACEUTICALS, INC. (US) 2025-12-30 — — US disclosed
US-20250368657-A1 METHODS FOR INHIBITING FASCIN NOVITA PHARMACEUTICALS INC (US) 2025-12-04 — — US disclosed
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN CORNELL UNIVERSITY (US) 2025-10-30 — — US disclosed
WO-2010022177-A2 PRODRUGS OF METHYL HYDROGEN FUMARATE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE XENOPORT, INC. (US) 2010-02-25 — — WO disclosed
US-20080221108-A1 Anthranilic Acid Derivatives As Hm74A Receptor Agonists SMITHKLINE BEECHAM CORPORATION 2008-09-11 — — US disclosed
EP-1951746-A1 SOLUTION-PHASE SYNTHESIS OF LEUPROLIDE AND ITS INTERMEDIATES NANOKEM S.A. (UY) 2008-08-06 — — EP disclosed
EP-1848699-A1 ANTHRANILIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2007-10-31 — — EP disclosed
WO-2007059922-A1 SYNTHESIS OF CARBON ACID AMIDES SYNTHACON GMBH (DE) 2007-05-31 — — WO disclosed
WO-2007059921-A1 SOLUTION-PHASE SYNTHESIS OF LEUPROLIDE AND ITS INTERMEDIATES NANOKEM S.A. (UY) 2007-05-31 — — WO disclosed
WO-2006085112-A1 ANTHRANILIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2006-08-17 — — WO disclosed
EP-1670749-A1 2-SUBSTITUTED BENZOIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2006-06-21 — — EP disclosed
WO-2005016870-A1 2-SUBSTITUTED BENZOIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2005-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 DGAT1 3742/4885KMT2A 1584/4885MAPT 2925/4885
US-12577236-B2 Processes for preparation of Tezacaftor CYP4A11, F9, CYP3A4 DGAT1 2456/4885KMT2A 398/4885MAPT 3497/4885
US-12508245-B2 Co-therapies including a metastasis inhibitor PDCD1, CD274, PDCD4 DGAT1 4238/4885KMT2A 2544/4885MAPT 148/4885
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN FSCN1, MTPN, MYOF DGAT1 673/4885KMT2A 4757/4885MAPT 352/4885
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM SGMS2, SGMS1, GBA2 DGAT1 784/4885KMT2A 1936/4885MAPT 671/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 DGAT1 3071/4885KMT2A 1769/4885MAPT 3405/4885
US-20250368657-A1 METHODS FOR INHIBITING FASCIN FSCN1, NLN, TNNI3 DGAT1 1790/4885KMT2A 4603/4885MAPT 1238/4885
US-20080221108-A1 Anthranilic Acid Derivatives As Hm74A Receptor Agonists ANTXR2, GPR84, HCAR1 DGAT1 4187/4885KMT2A 1142/4885MAPT 4865/4885
US-20260124177-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR CCR10, CCR4, OGFR DGAT1 3542/4885KMT2A 3991/4885MAPT 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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