SCHEMBL21073734

SCHEMBL21073734

CN(C)C(n1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.51
▸ KMT2A Q03164 4/20 0.47
▸ MAPT P10636 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ GAA P10253 11/20 0.43
▸ MGAM O43451 10/20 0.43
▸ AMY1A P0DUB6 10/20 0.43
▸ SI P14410 10/20 0.43
▸ MGAM2 Q2M2H8 10/20 0.43
▸ F2 P00734 2/20 0.43
▸ SLC9A1 P19634 2/20 0.43
▸ HPGD P15428 1/20 0.43
▸ KCNMA1 Q12791 1/20 0.40
▸ F12 P00748 5/20 0.40
▸ POLB P06746 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3893181 0.94 DGAT1 (0.57) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL1971917 0.91 DGAT1 (0.51) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL21904738 0.91 DGAT1 (0.51) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL21904737 0.89 DGAT1 (0.49) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL2732055 0.81 DGAT1 (0.49) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL29031460 0.81 DGAT1 (0.49) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL20591983 0.80 TUBB4A (0.41) —
SCHEMBL29369659 0.80 TUBB4A (0.41) —
SCHEMBL29538691 0.80 TUBB4A (0.41) DGAT1KMT2AMAPTKDM4EALDH1A1
SCHEMBL29475401 0.79 PKM (0.41) MAPTKDM4EHTTKCNMA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2025-05-01 — — US claimed
US-20240360147-A1 Process for Synthesizing Naphthyridine Derivatives and Intermediates Thereof AMGEN INC. 2024-10-31 — — US claimed
EP-4396170-A1 PROCESS FOR SYNTHESIZING NAPHTHYRIDINE DERIVATIVES AND INTERMEDIATES THEREOF Amgen Inc. (US) 2024-07-10 — — EP claimed
WO-2023141693-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
WO-2023141692-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
WO-2023034786-A1 PROCESS FOR SYNTHESIZING NAPHTHYRIDINE DERIVATIVES AND INTERMEDIATES THEREOF AMGEN INC. (US) 2023-03-09 — — WO claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-20250368657-A1 METHODS FOR INHIBITING FASCIN NOVITA PHARMACEUTICALS INC (US) 2025-12-04 — — US disclosed
US-12365649-B2 Process for the preparation of brivaracetam ALIVUS LIFE SCIENCES LIMITED (IN) 2025-07-22 — — US disclosed
US-12297226-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2025-05-13 — — US disclosed
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2025-05-01 — — US disclosed
US-20220380763-A1 NUCLEIC ACID DELIVERY ENHANCER NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2022-12-01 — — US disclosed
EP-4049664-A1 NUCLEIC ACID DELIVERY ENHANCER National University Corporation Kochi University (JP) 2022-08-31 — — EP disclosed
US-20220233673-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2022-07-28 — — US disclosed
EP-3999094-A1 A UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-TARGETING PEPTIDE Rigshospitalet (DK) 2022-05-25 — — EP disclosed
WO-2022049604-A1 PROCESS FOR PREPARING REVEFENACIN AND INTERMEDIATES THEROF CIPLA LIMITED (IN) 2022-03-10 — — WO disclosed
WO-2022040473-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2022-02-24 — — WO disclosed
US-20190194246-A1 SOLID PHASE PEPTIDE SYNTHESIS CEM CORPORATION (US) 2019-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360147-A1 Process for Synthesizing Naphthyridine Derivatives and Intermediates Thereof NME1, NPM1, NME2 DGAT1 2387/4885KMT2A 2878/4885MAPT 3408/4885
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 DGAT1 3742/4885KMT2A 1584/4885MAPT 2925/4885
US-12577236-B2 Processes for preparation of Tezacaftor CYP4A11, F9, CYP3A4 DGAT1 2456/4885KMT2A 398/4885MAPT 3497/4885
US-20220380763-A1 NUCLEIC ACID DELIVERY ENHANCER NXF1, WASF2, NUTF2 DGAT1 2828/4885KMT2A 2709/4885MAPT 4484/4885
US-12297226-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, ACE DGAT1 2298/4885KMT2A 3890/4885MAPT 876/4885
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM SGMS2, SGMS1, GBA2 DGAT1 784/4885KMT2A 1936/4885MAPT 671/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 DGAT1 3071/4885KMT2A 1769/4885MAPT 3405/4885
US-12365649-B2 Process for the preparation of brivaracetam CYP2C19, CYP2B6, POR DGAT1 3271/4885KMT2A 1272/4885MAPT 3452/4885
US-20250368657-A1 METHODS FOR INHIBITING FASCIN FSCN1, NLN, TNNI3 DGAT1 1790/4885KMT2A 4603/4885MAPT 1238/4885
US-20190194246-A1 SOLID PHASE PEPTIDE SYNTHESIS VIP, SPPL2B, PTMS DGAT1 4368/4885KMT2A 4327/4885MAPT 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback