SCHEMBL2959934

SCHEMBL2959934

CC(=O)ON1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.64
KDM4E B2RXH2 8/20 0.64
HPGD P15428 7/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
HSD17B10 Q99714 3/20 0.64
ERCC1 P07992 1/20 0.55
FEN1 P39748 1/20 0.55
ERCC4 Q92889 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
MAPT P10636 3/20 0.50
CYP1A2 P05177 1/20 0.50
AKR1B1 P15121 1/20 0.50
ALOX15 P16050 1/20 0.50
CYP1B1 Q16678 1/20 0.50
HTT P42858 1/20 0.49
HEXA P06865 1/20 0.47
HEXB P07686 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8087952 0.89 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL8088866 0.85 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL13898970 0.84 KDM4E (0.57) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5865397 0.83 NPC1 (0.50) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL859822 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL29838651 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL13898509 0.83 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL27400027 0.83 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL7709436 0.82 KLK7 (0.61) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL11706176 0.82 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084090-B2 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-01 US claimed
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US claimed
CN-106800549-A A kind of imidazoles acid naphthalimide base ethyl ester compound and application thereof 青岛科技大学 2017-06-06 CN disclosed
US-20170130028-A1 RUBBER COMPOSITION AND VULCANIZATION AID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-11 US disclosed
US-20170130028-A1 RUBBER COMPOSITION AND VULCANIZATION AID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-11 US disclosed
US-20170043931-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2017-02-16 US disclosed
US-20170043931-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2017-02-16 US disclosed
US-9505541-B2 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2016-11-29 US disclosed
US-20150217923-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2015-08-06 US disclosed
EP-1433527-B1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS DAICEL CHEM (JP) 2013-11-06 EP disclosed
US-20130023609-A1 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2013-01-24 US disclosed
US-7524986-B2 Methods for producing aromatic carboxylic acids DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-28 US disclosed
US-20070191634-A1 Methods for producing aromatic carboxylic acids DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-08-16 US disclosed
EP-1734029-A1 PROCESS FOR PRODUCING AROMATIC CARBOXYLIC ACID Daicel Chemical Industries, Ltd. (JP) 2006-12-20 EP disclosed
US-20060229196-A1 Catalyst comprising n-substituted cyclic imide compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-10-12 US disclosed
US-7084090-B2 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-01 US disclosed
EP-1433527-A1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2004-06-30 EP disclosed
US-20040053778-A1 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-03-18 US disclosed
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US disclosed
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191634-A1 Methods for producing aromatic carboxylic acids PAH, AHR, HAO2 ALDH1A1 329/4885KDM4E 949/4885HPGD 173/4885
US-20060229196-A1 Catalyst comprising n-substituted cyclic imide compound and process for producing organic compounds using the catalyst NOS2, NOS1, NOS3 ALDH1A1 1553/4885KDM4E 3183/4885HPGD 273/4885
US-20170130028-A1 RUBBER COMPOSITION AND VULCANIZATION AID CCNA1, RCN1, RER1 ALDH1A1 4162/4885KDM4E 3090/4885HPGD 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.