Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749524 | 0.88 | CYP3A4 (0.55) | CTSKCTRB1ACEACE2SMN1; SMN2 | |
| SCHEMBL29603779 | 0.88 | CYP3A4 (0.55) | CTSKCTRB1ACEACE2SMN1; SMN2 | |
| SCHEMBL7410773 | 0.85 | CTSL (0.47) | CTSKCTRB1ACEACE2L3MBTL1 | |
| SCHEMBL20704854 | 0.85 | CTSK (0.53) | CTSKCTRB1ACEACE2L3MBTL1 | |
| SCHEMBL10283715 | 0.84 | CTRB1 (0.52) | CTRB1ACACBCYP3A4MAPK1NPC1 | |
| SCHEMBL13285960 | 0.84 | CTRB1 (0.52) | CTRB1ACACBCYP3A4MAPK1NPC1 | |
| SCHEMBL4385669 | 0.83 | POLB (0.62) | CTSKACEACE2CYP2C19L3MBTL1 | |
| SCHEMBL3652453 | 0.83 | POLB (0.62) | CTSKACEACE2CYP2C19L3MBTL1 | |
| SCHEMBL12057567 | 0.82 | TLR2 (0.44) | CTSKACEACE2CTSL | |
| SCHEMBL844471 | 0.81 | ITGB3 (0.58) | CTSKACEACE2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983408-A1 | PHENETHYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS WITH AN N-1 BRANCHED GROUP | 3M Innovative Properties Company (US) | 2022-04-20 | — | — | EP | disclosed |