Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965628 | 0.85 | MTNR1A (0.46) | S1PR1 | |
| SCHEMBL1563972 | 0.84 | S1PR1 (0.57) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL3084328 | 0.84 | S1PR1 (0.55) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL5505756 | 0.84 | S1PR1 (0.63) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL1564063 | 0.83 | S1PR1 (0.54) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL1564052 | 0.82 | S1PR1 (0.61) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL1563280 | 0.82 | S1PR1 (0.52) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL2968163 | 0.82 | S1PR1 (0.56) | S1PR1NR4A2FFAR1 | |
| SCHEMBL1563997 | 0.82 | S1PR1 (0.58) | S1PR1MAOBNR4A2PRKXACVR1 | |
| SCHEMBL5505536 | 0.81 | S1PR1 (0.58) | S1PR1MAOBNR4A2PRKXACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617711-A1 | Amino alcohol derivatives, salts thereof and immunosuppressive agents | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7763752-B2 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KOHNO YASUSHI | 2009-06-18 | — | — | US | disclosed |
| US-7482491-B2 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1548003-A1 | AMINO ALCOHOL DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | AADAT, BCAT2, ADH1A | S1PR1 958/4885MAOB 3202/4885NR4A2 1780/4885 |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | ADH1A, TPMT, AADAT | S1PR1 703/4885MAOB 2584/4885NR4A2 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.