Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960835 | 0.85 | S1PR1 (0.56) | S1PR1 | |
| SCHEMBL27974256 | 0.82 | POLB (0.43) | MTNR1AMTNR1BMAPT | |
| SCHEMBL14012839 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BS1PR1SIRT2TUBB4A | |
| SCHEMBL1563959 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BSIRT2TUBB4ATUBB | |
| SCHEMBL1563614 | 0.74 | MTNR1A (0.42) | MTNR1AMTNR1BS1PR1SIRT2TUBB4A | |
| SCHEMBL27949329 | 0.72 | HPGD (0.50) | SIRT2 | |
| SCHEMBL13179951 | 0.72 | PPARA (0.43) | MTNR1AMTNR1BS1PR1 | |
| SCHEMBL4708636 | 0.70 | MTNR1A (0.46) | MTNR1AMTNR1BMAPT | |
| SCHEMBL47914 | 0.70 | APLNR (0.50) | MTNR1AMTNR1B | |
| SCHEMBL4819345 | 0.70 | SIRT2 (0.41) | SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617711-A1 | Amino alcohol derivatives, salts thereof and immunosuppressive agents | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7763752-B2 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KOHNO YASUSHI | 2009-06-18 | — | — | US | disclosed |
| US-7482491-B2 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1548003-A1 | AMINO ALCOHOL DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | AADAT, BCAT2, ADH1A | MTNR1A 3413/4885MTNR1B 2503/4885S1PR1 958/4885 |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | ADH1A, TPMT, AADAT | MTNR1A 2992/4885MTNR1B 2374/4885S1PR1 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.