Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4543521 | 0.87 | HSD11B1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL29612285 | 0.86 | CA2 (0.34) | GABRA1GABRB2CA2 | |
| Hydrochloric Acid SCHEMBL29612291 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27670358 | 0.81 | GABRA1 (0.31) | GABRA1GABRB2CA2 | |
| SCHEMBL27687666 | 0.79 | GABRA1 (0.32) | GABRA1GABRB2CA2 | |
| Hydrochloric Acid SCHEMBL29564499 | 0.79 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2525982 | 0.79 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2523909 | 0.79 | KIF11 (0.33) | — | |
| Hydrochloric Acid SCHEMBL2525067 | 0.78 | CA12 (0.36) | CA2 | |
| Hydrochloric Acid SCHEMBL29612287 | 0.78 | CA12 (0.36) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | claimed |