Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 2/20 | 0.86 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.69 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FPGS | Q05932 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL30051011 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL2693607 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29422840 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL31173596 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL7678398 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL79039 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL258787 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL1882912 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL4727836 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL30828726 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120131660-A | Composition and application thereof | 北京斯利安药业有限公司 | 2025-06-13 | — | — | CN | claimed |
| EP-4114399-A1 | FOLATE PREPARATIONS FOR THE TREATMENT OF OCULAR DISEASES | Aprofol AG (CH) | 2023-01-11 | — | — | EP | claimed |
| CN-115427046-A | Folic acid substance preparation for treating eye diseases | 阿普罗福尔公司 | 2022-12-02 | — | — | CN | claimed |
| CN-109939077-B | Controlled release preparation containing 5-methyltetrahydrofolic acid | 深圳奥萨制药有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-109864978-B | Sustained-release preparation of 5-methyltetrahydrofolic acid and preparation method thereof | 深圳奥萨制药有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-120131660-A | Composition and application thereof | 北京斯利安药业有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-117448293-A | Dihydrofolate reductase mutant and preparation method and application thereof, and preparation method of 6S-5-methyltetrahydrofolate calcium | 金达威生物技术(江苏)有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115427046-A | Folic acid substance preparation for treating eye diseases | 阿普罗福尔公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-109939077-B | Controlled release preparation containing 5-methyltetrahydrofolic acid | 深圳奥萨制药有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109864978-B | Sustained-release preparation of 5-methyltetrahydrofolic acid and preparation method thereof | 深圳奥萨制药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-2773355-B1 | METHODS, FORMULATIONS, AND KITS FOR RAPIDLY REPLETING FOLATE LEVELS IN WOMEN | SOUTH ALABAMA MEDICAL SCIENCE FOUND (US) | 2022-06-08 | — | — | EP | disclosed |