Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 2/20 | 0.86 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.69 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FPGS | Q05932 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL30051011 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL2693607 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29422840 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL31173596 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL7678398 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL79039 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29616390 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL1882912 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL4727836 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL30828726 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622913-B2 | Folate salts for medical use | APROFOL AG (CH) | 2026-05-12 | — | — | US | claimed |
| US-12419860-B2 | Time release sleep aid system | NIGHTWISE, LLC (US) | 2025-09-23 | — | — | US | claimed |
| US-20250255887-A1 | DIETARY NUTRIENT COMPOSITIONS | Natals, Inc. | 2025-08-14 | — | — | US | claimed |
| US-12318395-B2 | Ethinyl estradiol-β-cyclodextrin complex and process for preparing thereof | LABORATORIOS LEON FARMA, S.A. (ES) | 2025-06-03 | — | — | US | claimed |
| US-12234237-B2 | Folate salts | APROFOL AG (CH) | 2025-02-25 | — | — | US | claimed |
| US-12221445-B2 | Crystalline salts of 5-methyl-(6S)-tetrahydrofolic acid and amino ethyl esters | MERCK PATENT GMBH (DE) | 2025-02-11 | — | — | US | claimed |
| US-20240415810-A1 | TIME RELEASE SLEEP AID SYSTEM | NIGHTWISE, LLC | 2024-12-19 | — | — | US | claimed |
| US-12138266-B2 | Folate preparations | APROFOL AG (CH) | 2024-11-12 | — | — | US | claimed |
| US-12128057-B2 | Dietary nutrient compositions | Natals, Inc. (US) | 2024-10-29 | — | — | US | claimed |
| US-12128056-B2 | Dietary nutrient compositions | Natals, Inc. (US) | 2024-10-29 | — | — | US | claimed |
| CN-1032206-C | Process for preparing tetrahydrofolic acid | EPROVA AG (CH) | 1996-07-03 | — | — | CN | claimed |
| US-5457202-A | Resolution of 5-methyltetrahydrofolic acid | KNOLL AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | claimed |
| EP-0348641-B1 | Process for the preparation of tetrahydrofolates | EPROVA AG (CH) | 1995-06-21 | — | — | EP | claimed |
| EP-0455013-B1 | Ammoniumsalts of N(5)-methyl-5,6,7,8-tetrahydrofolic acid | SAPEC FINE CHEMICALS (CH) | 1995-06-21 | — | — | EP | claimed |
| EP-0612322-A1 | METHOD OF SEPARATING THE ENANTIOMERS OF 5-METHYL-TETRAHYDROFOLIC ACID | KNOLL AKTIENGESELLSCHAFT (DE) | 1994-08-31 | — | — | EP | claimed |
| WO-1993010118-A1 | METHOD OF SEPARATING THE ENANTIOMERS OF 5-METHYL-TETRAHYDROFOLIC ACID | KNOLL ATIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | claimed |
| EP-0455013-A1 | Ammoniumsalts of N(5)-methyl-5,6,7,8-tetrahydrofolic acid | Cerbios-Pharma S.A. (CH) | 1991-11-06 | — | — | EP | claimed |
| US-5006655-A | Process for the preparation of tetrahydrofolates | EPROVA AG (CH) | 1991-04-09 | — | — | US | claimed |
| CN-1038813-A | The method for preparing tetrahydrofolate | EPROVA AG (CH) | 1990-01-17 | — | — | CN | claimed |
| EP-0348641-A2 | Process for the preparation of tetrahydrofolates | EPROVA Aktiengesellschaft (CH) | 1990-01-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622913-B2 | Folate salts for medical use | FOLR2, FOLR1, MTHFD1 | MTHFD1 3/4885DHFR 11/4885SOST 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.